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What to Expect

What side effects should I expect from TB-500?

Updated 2026-05-05

TB-500 is generally quiet on the body. Most users report mild injection-site redness, brief lightheadedness, or a flushed feeling for 10-15 minutes after a shot. Some report fatigue or brain fog the day of injection, which usually fades by day two. There are no published long-term human safety trials, and the bigger TB-500 dose (2.5 mg per shot) is sometimes harder on the body than smaller peptide doses.

IfIf you feel wiped out the day of your shot
Thenthen move your injection to evening or before bed
IfIf the injection site stings for hours
Thenthen warm the vial in your hand for 30 seconds before drawing - cold solution stings more
IfIf you have a history of cancer
Thenthen talk to a prescriber first - TB-500 affects cell migration and that signal in people with cancer history is unstudied
IfIf you stack with BPC-157
Thenthen introduce them one at a time - that way you know which peptide caused any reaction
Key facts
  • No randomized human trials of TB-500 safety have been published as of 2026
  • Most community-reported side effects are mild: injection-site redness, brief flushing, occasional fatigue
  • TB-500 is dosed in milligrams (not micrograms), so each shot is much higher mass than peptides like BPC-157
  • TB-500 is on the World Anti-Doping Agency banned list; it can show on a drug test
  • Long-term safety, cancer-promotion risk, and immune effects are not characterized in humans
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