Basics & Technique
How do I reconstitute a 10 mg PT-141 vial?
Updated 2026-05-05
Add 1 mL of bacteriostatic water to a 10 mg PT-141 vial. That gives you 10 mg per mL. On a U-100 insulin syringe, 10 units equals 1 mg of PT-141, and 17.5 units equals 1.75 mg (the standard scouting dose). Take the shot 30-60 minutes before sex. Pour water down the vial wall, swirl, and store in the fridge.
IfIf your dose is 1 mg (lowest scouting dose)
Thenthen draw 10 units on a U-100 insulin syringe
IfIf your dose is 1.75 mg (standard)
Thenthen draw 17 or 18 units on a U-100 insulin syringe
IfIf you feel nausea or flushing the first time
Thenthen drop the next dose to 0.5-1 mg and titrate up slowly
IfIf you have high blood pressure
Thenthen talk to a prescriber before using PT-141 - it can raise blood pressure for several hours
Key facts
- 10 mg vial + 1.0 mL bac water = 10 mg/mL concentration
- On a U-100 syringe at 10 mg/mL, 1 unit = 100 mcg
- Vyleesi (the prescription brand) uses an autoinjector at 1.75 mg - that is the reference dose
- Most users scout-dose at 0.5-1 mg first to gauge nausea and flushing
- Effect window is typically 4-6 hours; do not redose the same day
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