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Basics & Technique

How do I mix a 10 mg retatrutide vial?

Updated 2026-05-04

Add 1.0 mL of bacteriostatic water to a 10 mg retatrutide vial. That gives you 10 mg per mL, or 1 mg for every 10 units on a U-100 insulin syringe. A 2 mg dose is 20 units. A 4 mg dose is 40 units. Tilt the bac water down the vial wall, swirl gently, and let it sit 2 minutes until clear. Store the mixed vial in the fridge and use within 28 days.

IfIf your dose is 2 mg
Thenthen draw 20 units on a U-100 insulin syringe
IfIf your dose is 4 mg
Thenthen draw 40 units on a U-100 insulin syringe
IfIf you only have a 1 mL syringe (not insulin)
Thenthen 0.2 mL = 2 mg, 0.4 mL = 4 mg
IfIf the powder is still floating after 2 minutes
Thenthen swirl gently again - never shake hard, that can damage the peptide
Key facts
  • 10 mg vial + 1.0 mL bac water = 10 mg/mL concentration
  • On a U-100 insulin syringe, every 10 units equals 1 mg
  • Retatrutide titration in trials stepped 2 mg, 4 mg, 8 mg, 12 mg weekly with 4 weeks at each step
  • Mixed vial keeps in the fridge for ~28 days
  • Bacteriostatic water is the standard diluent; sterile water is acceptable but the vial must be used in 24 hours
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